Cysticercus Antibody (IgG), ELISA, CSF
Use
Cysticercosis is a tissue infection with larval cysts of the pork tapeworm, Taenia solium, where the patient serves as an intermediate host. The most common manifestation is neurocysticercosis, occurring when the larvae invade the central nervous system, causing symptoms like seizures and chronic meningitis. Detection of intrathecally produced specific antibodies aids in the diagnosis of central nervous system infections. The test identifies antibodies directed against the parasite, although antibodies to other infections like echinococcosis may cross-react.
Special Instructions
Confirmation of positive cysticercus ELISA results by IgG antibody Western blot is recommended due to potential cross-reactivity with antibodies against other parasitic infections such as echinococcosis.
Limitations
Antibodies to other parasitic infections, especially echinococcosis, may cross-react in the cysticercus IgG ELISA. Interpretation of results may be complicated by low antibody levels in CSF, passive transfer of antibody from blood, and contamination via bloody taps. It is advised to confirm positive ELISA results with a cysticercus IgG antibody Western blot.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 35391-2
- 35391-2
Result Turnaround Time
9 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.1 mL
Container
Sterile container
Collection Instructions
Submit 1 mL of spinal fluid (CSF) in a sterile, plastic screw-cap vial. Refrigerate specimen after collection and ship at refrigerated temperature.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icteric, bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |