Cystinuria Profile, Quantitative, 24 Hour, Urine
Use
Provides a biochemical diagnosis of cystinuria through measurement of cystine, lysine, ornithine, and arginine in a 24‑hour urine collection; useful in patients with suspected cystinuria for evaluation of renal excretion of dibasic amino acids ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/Overview/8376?utm_source=openai)).
Special Instructions
Requires submission of 24‑hour urine volume and patient age; include family history, clinical condition, diet, and drug therapy. If ordering on paper, use Biochemical Genetics Test Request form (T798). Urine preservative (diazolidinyl urea) preferred; alternate storage includes refrigeration during collection ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/Overview/8376?utm_source=openai)).
Limitations
Test was developed and validated by Mayo Clinic Labs under CLIA but is not FDA cleared or approved. No significant cautionary statements noted ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/Overview/8376?utm_source=openai)).
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 90785-7
- 13362-9
- 3167-4
- 13966-7
- 25464-9
- 25491-2
- 25322-9
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL aliquot from 24‑hour urine
Minimum Volume
1 mL
Container
Urine Tubes, 10 mL (T068)
Collection Instructions
Collect before intravenous pyelogram; add 5 g diazolidinyl urea (Germall) at start of collection (if unavailable, refrigerate during collection); collect for 24 hours; mix well before taking 5 mL aliquot
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 70 days |