D-Dimer, Plasma
Use
The D-dimer test is useful for the diagnosis of intravascular coagulation and fibrinolysis, known as disseminated intravascular coagulation, when combined with clinical information and other laboratory tests like platelet count, clottable fibrinogen, and clotting time assays. It also helps in the exclusion of acute pulmonary embolism or deep vein thrombosis diagnosis, particularly when results are combined with clinical information, including pretest disease probability.
Special Instructions
This test is not directly orderable and is included as part of a profile or reflex testing. It is included in profiles such as Bleeding Diathesis Profile, Thrombophilia Profile, Prolonged Clot Time Profile, Disseminated Intravascular Coagulation Profile, and Lupus Anticoagulant Profile.
Limitations
Lipemia can cause an overestimation of the D-dimer level, and results from lipemic specimens should be interpreted with caution. The presence of rheumatoid factor above 50 IU/mL may also lead to an overestimation. Increased D-dimer values are not specific to any disease and can be elevated due to conditions like recent surgery, bleeding, trauma, or thromboembolism, and are associated with pregnancy, malignancy, or liver disease.
New York Approved
Methodology
Immunoassay (Latex Immunoassay (LIA))
Biomarkers
LOINC Codes
- 48067-3
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Causes for Rejection
Gross hemolysis, Gross lipemia, Gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |