Dandelion, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to dandelion by identifying the allergen responsible for eliciting signs and symptoms in the patient. It is also helpful in defining allergens responsible for allergic responses and/or anaphylactic episodes, confirming sensitization prior to immunotherapy, and investigating the specificity of allergic reactions to various allergens such as insect venom, drugs, or chemicals. Testing for IgE antibodies provides an indication of the immune response to allergens that may be associated with allergic diseases.
Special Instructions
Testing for IgE antibodies is not useful in patients who have previously undergone immunotherapy to determine if residual clinical sensitivity exists or in patients where medical management doesn't rely on identifying allergen specificity. Specimen volume for processing is 0.5 mL for every 5 allergens requested in the test.
Limitations
The presence of measurable levels of IgE antibodies in some individuals may not indicate significant clinical sensitivity. False positives might occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. Test results must be interpreted within a clinical context to prevent diagnostic confusion.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6097-0
- 6097-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL per 5 allergens
Minimum Volume
0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Specimen types: Gross hemolysis okay, Gross lipemia okay.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
