Dextromethorphan (DM), Serum
Use
Dextromethorphan testing is primarily used to monitor therapeutic drug concentrations, optimize dosage, and assess compliance in patients who are administered dextromethorphan as part of their treatment regimen. It may also be employed in toxicology screenings to detect overdose or improper use.
Special Instructions
For optimal results, collect specimens using the specified tubes, avoiding gel tubes which may interfere with the test accuracy. Ensure proper storage conditions before transport to maintain specimen stability.
Limitations
The test may be subject to interference from hemolysis, lipemia, and icterus, affecting the accuracy of results. Certain substances or medications could potentially cause cross-reactivity, altering the measured concentrations. Results should be interpreted in the context of the overall clinical picture and should not be the sole factor in therapeutic decision making.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 13623-4
- 13623-4
Result Turnaround Time
5-11 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
0.25 mL
Container
Green-top (sodium heparin) tube, plastic vial
Collection Instructions
Spin down and send 2 mL sodium heparin refrigerated in a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 180 days |