Dihhydrotestosterone, Serum
Use
This test quantifies dihydrotestosterone (DHT) levels in serum, aiding in the assessment of androgen excess or deficiency. Dihydrotestosterone is a potent androgen that plays a critical role in male sexual development, and abnormal levels can be associated with various conditions such as male pattern baldness, prostate diseases, and certain endocrine disorders. Measuring serum DHT provides important insights into the body's androgen status and helps guide clinical management in cases of suspected disordered testosterone metabolism or androgen-secreting neoplasms.
Special Instructions
Not provided.
Limitations
This test is specific for DHT in the serum and is not intended for use with other specimen types. Results may be affected by conditions that cause fluctuations in hormone levels or interfere with steroid metabolism, such as liver dysfunction or medication use. It is important to consider the clinical context and corroborate results with additional diagnostic information. False elevations can occur if samples are not properly handled or stored.
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Dihydrotestosterone
Analyte
LOINC Codes
- 1845-9
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red Top Tube
Collection Instructions
Collect blood in a plain red-top tube and allow it to clot. Centrifuge to separate serum, and transfer the serum into a labeled plastic vial.
Storage Instructions
Store the serum at refrigerated temperature. It is stable for 7 days when refrigerated and 30 days when frozen. Do not store at room temperature.
Causes for Rejection
Gross hemolysis or improper labeling of specimens may lead to rejection of the sample.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | unstable |
| Refrigerated | 7 days |
| Frozen | 30 days |