Diphtheria/Tetanus Antibody Panel, Serum
Use
The test is useful for assessing antibody response to tetanus and diphtheria toxoid vaccines and aiding in the evaluation of immunodeficiency. It is typically performed at least three weeks post-immunization to evaluate the immune system's response. The lack of an expected antibody response may indicate immunodeficiency, which could be congenital or acquired. It also helps monitor vaccination effectiveness at preventing these diseases.
Special Instructions
This test is not suitable for diagnosing tetanus infection. It is important to ensure proper specimen collection and handling, as improper procedures can lead to diagnostic confusion.
Limitations
The assay cannot provide conclusive proof regarding the protection status against diphtheria and tetanus or confirm the presence or absence of immunodeficiency. It should be confirmed with clinical evaluation and additional serological testing. Diagnosis of tetanus relies primarily on clinical observation.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 101791-2
- 26643-7
- 53935-3
- 45166-6
- 48654-8
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.8 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 30 days |
| Frozen | 30 days |