Disaccharidase Activity Panel, Tissue
Use
Disaccharidases in the small intestines are responsible for breaking down disaccharides into monosaccharides. A deficiency in one or more disaccharidase enzymes can result in an array of gastrointestinal symptoms, including intolerance to foods containing complex sugars, diarrhea, constipation, abdominal pain, cramping, gas, bloating, nausea, malnutrition, weight loss, or failure to thrive. These symptoms can lead to misdiagnosis or delayed diagnosis of disaccharide deficiencies.
Special Instructions
This test is not intended for carrier detection. Biopsy homogenates are retained for one month post-testing. If not ordering electronically, complete and send a Biochemical Genetics Patient Information form or a Gastroenterology and Hepatology Test Request form with the specimen.
Limitations
This test cannot distinguish between primary and secondary causes of disaccharidase deficiencies, which can vary due to genetic and mucosal damage causes. Neither primary nor secondary deficiencies can be speculated upon purely from test results.
New York Approved
Methodology
Automated Analyzer
Biomarkers
LOINC Codes
- 57765-0
- 81315-4
- 30372-7
- 30315-6
- 81314-7
- 81322-0
- 57779-1
- 18771-6
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Frozen)
Volume
5 mg
Minimum Volume
Not provided
Container
15 mL tissue tube
Collection Instructions
Place specimen in a tissue tube. The specimen should not be placed on gauze, filter paper, swabs/wooden sticks and should not have any saline, water, support, or embedding material added.
Storage Instructions
Freeze immediately after collection and ship frozen.
Causes for Rejection
Specimens sent in formaldehyde, saline, or any supportive media; Specimens placed on gauze, filter paper, foil, or swabs/wooden sticks
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 28 days |