Ehrlichia Antibody Panel, Serum
Use
The Ehrlichia Antibody Panel, Serum is useful as an adjunct in diagnosing infections caused by Anaplasma phagocytophilum or Ehrlichia chaffeensis. It is also used in seroepidemiological surveys to determine the prevalence of these infections in specific populations. Anaplasma phagocytophilum is primarily transmitted by Ixodes ticks and is associated with human granulocytic anaplasmosis, whereas Ehrlichia chaffeensis is transmitted by Amblyomma ticks and is linked to human monocytotropic ehrlichiosis. These infections can vary from subclinical to life-threatening, particularly in immunocompromised patients.
Special Instructions
Not provided.
Limitations
Serology results may be negative during the acute phase of infection, typically within the first 7 days post-symptom onset. In such cases, nucleic acid amplification testing is recommended. IgG antibodies may persist for months or years, therefore, a single positive result must be interpreted in conjunction with clinical findings to differentiate between recent and past infections. Other Ehrlichia species may not be detected by this assay, and factors like improper specimen collection can affect results.
New York Approved
Methodology
Immunoassay (Immunofluorescence Assay (IFA))
Biomarkers
LOINC Codes
- 77165-9 - A phagocyt + E chaff Ab.IgG Pnl Titr Ser
- 23877-4 - A phagocytoph IgG Titr Ser IF
- 47405-6 - E chaffeensis IgG Titr Ser IF
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
Not provided
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |