Ehrlichia/Babesia Antibody Panel, Immunofluorescence, Serum
Use
The Ehrlichia/Babesia Antibody Panel is used to detect antibodies as an aid in the diagnosis of infections with Anaplasma phagocytophilum, Ehrlichia chaffeensis, and Babesia microti. These infections are typically transmitted through tick bites and can lead to conditions such as human granulocytic anaplasmosis, human monocytotropic ehrlichiosis, and babesiosis. This panel helps in understanding the prevalence and spread of these tick-borne diseases in specific populations through seroepidemiological surveys.
Special Instructions
Not provided.
Limitations
The test may demonstrate nonreactive results during the acute phase, when PCR testing is recommended. False positives can occur due to previous episodes of the infections, as antibodies can remain detectable long after the infection has cleared. Additionally, performance characteristics have not been established for hemolyzed or lipemic specimens, which can lead to diagnostic confusion.
Methodology
Immunoassay (Immunofluorescence Assay (IFA))
Biomarkers
Anaplasma phagocytophilum
MicroorganismBabesia microti
MicroorganismEhrlichia chaffeensis
Microorganism
LOINC Codes
- 101409-1 - Tick IgG Ab Pnl Ser
- 23877-4 - A phagocytoph IgG Titr Ser IF
- 16117-4 - B microti IgG Titr Ser
- 47405-6 - E chaffeensis IgG Titr Ser IF
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |
