Elm, IgE, Serum

Casandra

Casandra Test Code MC57853Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID ELMCPT Code 86003

Clinical Use

Use

Establishing a diagnosis of an allergy to elm by defining the allergen responsible for eliciting signs and symptoms. This test identifies allergens responsible for allergic responses and anaphylactic episodes, confirms sensitization before immunotherapy, and investigates the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. The results provide an indication of the immune response to allergens that could be associated with allergic disease.

Special Instructions

For the most accurate results, it is crucial to follow the specimen collection guidelines closely. Centrifuge and aliquot serum into a plastic vial immediately after collection. Use the Allergen Test Request form (T236) if not ordering electronically. The test is not useful in patients who have already undergone immunotherapy or whose medical management does not rely on allergen specificity.

Limitations

Testing for IgE antibodies may not be useful in individuals treated with immunotherapy to assess for residual clinical sensitivity. Results must be interpreted with caution as false positives can occur in patients with very high serum IgE levels due to nonspecific binding. It is essential to consider the clinical context as some individuals may exhibit IgE antibodies yet have clinically insignificant sensitivity to allergens.

Test Details

FDA Approved