Endometrial Stromal Tumors (EST), 7p15 (JAZF1), 6p21.32 (PHF1), 17p13.3 (YWHAE) Rearrangement, FISH, Tissue
Use
This test is useful for supporting the diagnosis of endometrial stromal tumors when used in conjunction with an anatomic pathology consultation. Endometrial stromal tumors (EST) are gastrointestinal neoplasms arising from the uterus and include benign endometrial stromal nodules (ESN) and endometrial stromal sarcomas (ESS).
Special Instructions
Not provided.
Limitations
The test is not FDA approved but has been developed consistent with CLIA requirements. Fixatives other than formalin may not be effective for FISH assays, and decalcified tissues may have a lower success rate. If the JAZF1 FISH report is not provided, testing and interpretation may be affected.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
No genes
GeneNo genes
GeneNo genes
Gene
LOINC Codes
- 102086-6 - Endometrial stromal tumor Tiss Doc FISH
- 50397-9 - Mol dx interp Bld/T Ql
- 69965-2 - Clinical cytogeneticist review
- 62356-1 - Chrom analy result (ISCN)
- 42349-1
- 31208-2 - Specimen source
- 80398-1 - Unique ID Current sample
- 85069-3 - Lab test method
- 48767-8 - Annotation comment Imp
- 18771-6 - Provider signing name
- 62364-5 - Test performance info Spec
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin-fixed, paraffin-embedded tumor tissue block
Collection Instructions
Submit a formalin-fixed, paraffin-embedded tumor tissue block. Alternative fixation methods can be acceptable; provide fixation method used.