Eosinophil Derived Neurotoxin, Serum
Use
This test is useful for evaluating patients suspected to have conditions associated with eosinophilia or hypereosinophilia. It is particularly valuable for evaluating patients with elevated peripheral blood eosinophil counts and managing patients with elevated eosinophil-derived neurotoxin in eosinophil-associated diseases. The test helps in assessing the activation status of eosinophils, and its results should be correlated with clinical evaluations and other diagnostic data.
Special Instructions
Serum must be aliquoted into a plastic vial within 12 hours of collection to prevent prolonged contact with the cell pellet, which can increase the concentration of eosinophil-derived neurotoxin. Serum cannot remain on gel or cells for longer than 12 hours.
Limitations
Elevated concentrations of eosinophil-derived neurotoxin are not diagnostic for any specific condition and should be evaluated alongside other laboratory and clinical information. Normal concentrations do not rule out the possibility of eosinophilia or hypereosinophilia.
New York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 100976-0
- 100976-0
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Serum gel tube or red top tube; aliquot into plastic vial
Collection Instructions
Within 12 hours of collection, centrifuge and aliquot serum into a plastic vial. Serum cannot sit on gel or cells for longer than 12 hours.
Causes for Rejection
Heat-treated specimen; if serum is on cell pellet or gel for more than 12 hours.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 21 days |