Ephedrine, Serum
Use
The Ephedrine test measures the serum concentration of ephedrine, a medication and decongestant that is commonly used to treat low blood pressure during anesthesia. It is important in monitoring therapeutic levels and potential toxicities in clinical settings. Ephedrine has stimulant properties and is used in certain sports and fitness supplement formulations, making its monitoring relevant for both medical and doping purposes.
Special Instructions
Ensure the specimen is light protected by using foil wrapping if it is not inherently protected by its container. Avoid using plasma or serum gel tubes as they are not acceptable for testing.
Limitations
This test is specific to serum levels of ephedrine and may not reflect tissue or compartmental differences of the drug distribution. Results can be affected by improper specimen handling, such as exposure to light or incorrect tube types, like gel separators, which are not acceptable. Interpretation should consider patient's clinical context and possible cross-reactivities with similar compounds.
Methodology
Mass Spectrometry (GC-EC)
Biomarkers
LOINC Codes
- 3591-5
- 3591-5
Result Turnaround Time
7-11 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
0.6 mL
Container
Plastic vial
Collection Instructions
Draw blood in a green-top sodium heparin tube. Spin down and send sodium heparin plasma refrigerated. Plasma gel tube not acceptable. If not light protected, foil wrap specimen.
Storage Instructions
Refrigerated preferred, ambient for short durations, frozen for long durations; all require light protection.
Causes for Rejection
EDTA tubes, gel separator tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 180 days |
