Epstein-Barr Virus (EBV), Molecular Detection, PCR, Varies
Use
This test is useful for the rapid qualitative detection of Epstein-Barr virus (EBV) DNA in specimens. It aids in the diagnosis of diseases caused by EBV, such as infectious mononucleosis, Burkitt lymphoma, and central nervous system (CNS) diseases like primary CNS lymphoma in AIDS patients. Detection of EBV DNA in cereborspinal fluid supports CNS disease diagnosis due to the virus.
Special Instructions
This test should not be used to screen asymptomatic patients. Specimen source information, including the main anatomical site, is required for successful testing. If not ordered electronically, complete and send one of the specified forms with the specimen.
Limitations
A negative result does not eliminate the possibility of an EBV infection of the CNS. This assay may detect viremia or viral shedding in asymptomatic individuals, and the results must be interpreted in the context of the patient's clinical picture. Clotted or improperly handled specimens will be rejected.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
LOINC Codes
- 5005-4
- 31208-2
- 5005-4
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Body Fluid
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Sterile screwcap 5-mL plastic vial or sterile container
Collection Instructions
Do not centrifuge.
Causes for Rejection
Clotted specimens, calcium alginate-tipped swab, wood swab, transport swab containing gel, formalin-fixed and paraffin-embedded tissues, heat-inactivated specimens, dry/flocked ESwabs
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 7 days |