Estrone, Serum
Use
As part of the diagnosis and workup of precocious and delayed puberty in females and, to a lesser degree, males. Diagnostic workup for suspected disorders of sex steroid metabolism (e.g., aromatase deficiency). Assists in assessing fracture risk in postmenopausal women and older men. Monitors low-dose female hormone replacement therapy and antiestrogen therapy such as aromatase inhibitor therapy.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the FDA. The performance characteristics were determined by Mayo Clinic consistent with CLIA requirements. Assay interference may occur due to high lipid content. Serum gel/SST tubes are not acceptable.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Estrone
Analyte
LOINC Codes
- 2258-2 - Estrone SerPl-mCnc
- 2258-2 - Estrone SerPl-mCnc
Result Turnaround Time
2-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.2 mL
Minimum Volume
0.7 mL
Container
Red top, plastic vial for submission
Collection Instructions
Centrifuge and aliquot into a plastic vial within 2 hours of collection.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus are acceptable
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |