Ethylene Oxide, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to ethylene oxide and defining the allergen responsible for eliciting signs and symptoms. It helps identify allergens responsible for allergic responses and/or anaphylactic episodes, confirms sensitization prior to beginning immunotherapy, and investigates the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon identification of allergen specificity.
Special Instructions
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Testing for IgE antibodies may not be useful in patients previously treated with immunotherapy, as it may not determine if residual clinical sensitivity exists. Additionally, in patients where medical management does not depend on identification of allergen specificity, testing may not add value. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6112-7
- 6112-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |