Factor II Inhibitor Profile, Technical Interpretation
Use
The test provides a technical interpretation of inhibitor to factor II testing. Coagulation factor inhibitors can develop in patients who are congenitally deficient in a specific factor due to replacement therapy, spontaneously due to various medical conditions such as postpartum state, immunologic disorders, certain antibiotic therapies, some malignancies, and in older populations. The inhibitors of factor VIII coagulant activity are the most commonly occurring specific factor inhibitors.
Special Instructions
This test is not useful for detecting a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors. The test is only orderable as part of a profile; see 2INHE / Factor II Inhibitor Evaluation, Plasma for more details.
Limitations
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor, such as factors VIII or IX. Factors indicative of such inhibitors may not be recognized by this assay directly.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 69049-5
- 69049-5
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Na Cit
Causes for Rejection
Gross hemolysis, Gross lipemia, Gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |