Factor IX Inhibitor Screen, Plasma
Use
The Factor IX Inhibitor Screen is used to detect the presence of specific factor inhibitors directed against coagulation factor IX. Such inhibitors can develop due to multiple transfusion exposures in hemophiliacs, certain disease states, or as a side effect of specific medications. Non-specific inhibitors may prolong tests like prothrombin time and activated partial thromboplastin time. This assay is crucial for identifying qualitative inhibitors to coagulation factors in patients.
Special Instructions
This test is not orderable directly and is typically ordered as a reflex test. For more information, refer to related tests: 9INHE / Factor IX Inhibitor Evaluation, Plasma; ALUPP / Lupus Anticoagulant Profile, Plasma; ALBLD / Bleeding Diathesis Profile, Limited, Plasma; APROL / Prolonged Clot Time Profile, Plasma. See the Coagulation Guidelines for Specimen Handling and Processing for more detailed instructions.
Limitations
Occasionally, a potent lupus-like anticoagulant may cause false-positive results for specific factor inhibitors, such as factors VIII or IX. It is important to account for this possibility when interpreting results. The test may not be suitable for patients already undergoing anticoagulant therapy, as this could interfere with results.
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 30086-3
- 30086-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
2 mL
Container
Plasma Na Cit
Collection Instructions
Refer to Coagulation Guidelines for Specimen Handling and Processing.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |
