Factor X Inhibitor Screen, Plasma
Use
This test is useful for detecting the presence of a specific factor inhibitor directed against coagulation factor X. It helps to identify an inhibitor to a specific coagulation factor, which can arise due to multiple exposures from transfusions, certain disease states, or drug-induced conditions. Non-specific inhibitors may also prolong screening tests like prothrombin time and activated partial thromboplastin time. The test qualitatively identifies these inhibitors in patients.
Special Instructions
This test is only orderable as a reflex based on other coagulation profiles including Factor X Inhibitor Evaluation, Bleeding Diathesis Profile, Limited, and Prolonged Clot Time Profile. It's important to follow the Coagulation Guidelines for Specimen Handling and Processing to ensure specimen integrity.
Limitations
A potent lupus-like anticoagulant may cause false-positive results for specific factor inhibitors, such as factor VIII or IX. This could lead to diagnostic confusion, and inappropriate specimen collection or handling could impact results. The modified nature of this test indicates that it has not been cleared by the US FDA, although its performance characteristics were determined in a CLIA-compliant manner by Mayo Clinic.
New York Approved
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 39556-6
- 39556-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
2 mL
Collection Instructions
Refer to Coagulation Guidelines for Specimen Handling and Processing available at Mayo Clinic Laboratories.
Causes for Rejection
Gross hemolysis, gross lipemia, and gross icterus will lead to rejection.
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |