Factor XI Inhibitor Profile, Professional Interpretation
Use
Factor XI inhibitors typically arise in patients with congenital factor XI deficiency (hemophilia C) or after infusion of fresh frozen plasma or factor XI concentrates. This test is useful to detect and quantify inhibitors to coagulation factor XI, offering a critical role in diagnosing and managing patients with factor XI deficiency or those who develop inhibitors after plasma infusion.
Special Instructions
This test is only orderable as a reflex through the primary test 11INE (Factor XI Inhibitor Evaluation, Plasma). For further inquiries, contact Mayo Clinic Laboratories customer service.
Limitations
The test may not be appropriate for patients with non-plasma samples. Improper specimen collection, handling, and processing may lead to inaccurate results. Do not use this test for initial screening purposes; it's designed as part of a specialized diagnostic workup for hemophilia C and related inhibitors.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 69049-5
- 69049-5
- 18771-6
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Na Cit
Storage Instructions
Transport specimen in frozen state; ensure it remains frozen during transport to the laboratory.
Causes for Rejection
Specimens not kept frozen within the specified stability period may be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |