Factor XI Inhibitor Screen, Plasma
Use
The Factor XI Inhibitor Screen is used to detect the presence of a specific inhibitor directed against coagulation factor XI. This test aids in identifying an inhibitor to a specific coagulation factor which may arise due to multiple exposures from transfusions in patients deficient in that factor, in response to specific disease states, or may be drug-induced. Non-specific inhibitors may also be present in patients and prolong certain screening tests such as prothrombin time and activated partial thromboplastin time.
Special Instructions
Not provided.
Limitations
Potent lupus-like anticoagulants may cause false-positive results for a specific factor inhibitor such as factor VIII or IX. The test consists of measuring factor XI activity before and after incubation of a mixture of normal plasma and patient's plasma. The presence of an indication of a factor XI inhibitor is determined by comparing the factor XI activity results and the calculated expected values.
New York Approved
Methodology
Other
Biomarkers
Factor XI activity
Analyte
LOINC Codes
- 80603-4 - Fact XI Inhib PPP Ql
- 80603-4 - Fact XI Inhib PPP Ql
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
2 mL
Container
Plasma Na Cit
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |