Fetomaternal Bleed, New York, Blood
Use
This test is useful for determining the volume of fetal-to-maternal hemorrhage to recommend an increased dose of Rh immune globulin. It is used only for specimens collected in New York state. Hemolytic disease of the newborn occurs when fetal red blood cells are coated with maternal IgG alloantibody, leading to accelerated destruction. Rh immune globulin (RhIG) is given to Rh-negative mothers pregnant with a Rh-positive fetus to prevent maternal immunization.
Special Instructions
This test is exclusive to specimens from New York State. For patients outside New York, the FMB / Fetomaternal Bleed, Flow Cytometry, Blood should be ordered. Specimen should arrive within 5 days of collection, preferably within 24-72 hours, and should not be centrifuged or aliquoted.
Limitations
Results must be interpreted with caution as conditions like hereditary persistence of fetal hemoglobin and thalassemia may result in falsely increased levels of fetal red blood cells. Differential RBC densities may impact results if aliquoted.
New York Approved
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 75308-7
- 55730-6
- 10331-7
- 55731-4
- 48767-8
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
6 mL
Minimum Volume
1 mL
Container
Lavender top (EDTA)
Collection Instructions
1. Fill evacuated tube as completely as possible. 2. Do not centrifuge. 3. Invert several times to mix blood. 4. Send specimen in original tube. Do not aliquot.
Storage Instructions
Refrigerated (preferred), Ambient storage acceptable
Causes for Rejection
Gross hemolysis, Gross lipemia, Gross icterus, Clotted blood
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 5 days |