Fibrinogen, Clauss, Plasma
Use
The Fibrinogen, Clauss test is used for detecting increased or decreased fibrinogen concentration, which may be of acquired or congenital origin. It is essential for monitoring the severity and treatment of disseminated intravascular coagulation and fibrinolysis. Fibrinogen, also known as Factor I, is a crucial plasma protein that participates in blood clotting. Variations in fibrinogen levels can indicate several health conditions, including acute or chronic inflammatory illnesses, liver disease, and nephrotic syndrome. Elevated fibrinogen levels are a risk factor for arterial and venous thromboembolism.
Special Instructions
This test is only orderable as part of a profile or reflex. Profiles that include this test are ALBLD, APROL, AATHR, ADIC, and ALUPP. The test must be sent to the lab Monday through Friday for processing.
Limitations
In patients with dysfibrinogenemias, this assay may provide spuriously low results. Elevated plasma levels of fibrin degradation products can also lower the detected fibrinogen levels with this method compared to end point methods. The presence of heparin above 1.0 U/mL may cause false results, making nephelometric or immunoassay methods preferable in such cases.
New York Approved
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 48664-7
- 48664-7
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Special Container
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |