Flurazepam (Dalmane) and Desalkylflurazepam
Use
This test provides quantitative analysis of flurazepam (Dalmane) and its metabolite, desalkylflurazepam, in plasma or serum. This can assist clinicians in monitoring therapeutic dosing, compliance, and assessing possible toxicity associated with flurazepam use. The test offers valuable data in clinical scenarios where benzodiazepine levels need precise measurement for effective therapeutic intervention.
Special Instructions
Not provided.
Limitations
The test cannot differentiate between levels from freshly administered flurazepam versus levels from drug accumulation. External factors such as co-administration of other drugs may affect flurazepam and desalkylflurazepam levels in unpredictable ways. Specimen integrity is crucial; improper handling and storage of samples may lead to inaccurate results. Hemolysis, lipemia, or icterus do not invalidate the sample but may affect results.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Desalkylflurazepam
AnalyteFlurazepam
Analyte
LOINC Codes
- 73826-0 - Flurazepam+Desalkyl SerPlBld Cfm-mCnc
- 46979-1 - Flurazepam SerPl Cfm-mCnc
- 46980-9 - Desalkylfluraz SerPl Cfm-mCnc
- 73826-0 - Flurazepam+Desalkyl SerPlBld Cfm-mCnc
Result Turnaround Time
5-9 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
0.3 mL
Container
Green-top (sodium heparin) tube; plasma gel tube unacceptable.
Collection Instructions
Draw blood in a green-top (sodium heparin) tube(s), spin down and send 2 mL sodium heparin plasma frozen in plastic vial.
Storage Instructions
Send frozen in plastic vial.
Causes for Rejection
NA
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 180 days |