Focused Pharmacogenomics Panel, Varies
Use
This panel provides a comprehensive analysis for multiple genes with strong drug phenotype associations. It assists in preemptive or reactive genotyping of patients for pharmacogenomic purposes, providing an assessment for genes with strong drug-gene associations, and aiding in the management of patients with complex medication regimens.
Special Instructions
Not provided.
Limitations
This test is not designed to provide specific dosing recommendations and is to be used as an aid to clinical decision making only. Results should be used in conjunction with other clinical and laboratory data. Specimens from patients who have received non-leukocyte reduced blood transfusions or allogeneic hematopoietic stem cell transplantation may contain donor DNA that could interfere with results.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
LOINC Codes
- 82118-1 - Pharmg result pnl
- 72884-0 - CYP1A2 allele Geno Bld/T
- 94254-0 - CYP1A2 gene prod met act Bld/T-Imp
- 57132-3 - CYP2C19 allele Geno Bld/T
- 79714-2 - CYP2C19 gene prod met act imp Bld/T-Imp
- 104667-1 - CYP2C19 Activity Score Bld/T
- 46724-1 - CYP2C9 allele Geno Bld/T
- 79716-7 - CYP2C9 gene prod met act imp Bld/T-Imp
- 104668-9 - CYP2C9 Activity Score Bld/T
- 40425-1 - CYP2D6 allele Geno Bld/T
- 79715-9 - CYP2D6 gene prod met act imp Bld/T-Imp
- 104669-7 - CYP2D6 Activity Score Bld/T
- 81139-8 - CYP3A4 allele Geno Bld/T
- 81145-5 - CYP3A4 gene prod met act Bld/T-Imp
- 81140-6 - CYP3A5 allele Geno Bld/T
- 79717-5 - CYP3A5 gene prod met act imp Bld/T-Imp
- 93412-5 - SLCO1B1 Mut Anl Bld/T
- 79722-5 - SLCO1B1 gene prod funct imp Bld/T
- 50722-8 - VKORC1 gene Mut Anl Bld/T
- 54451-0 - CYP2C9 & VKORC1 Bld/T-Imp
- 93197-2 - CYP4F2 c.1297G>A Geno Bld/T
- 93198-0 - 10q23 g.94645745G>A Geno Bld/T
- 69047-9 - Geneticist review
- 48767-8 - Annotation comment Imp
- 62364-5 - Test performance info Spec
- 18771-6 - Provider signing name
- 85069-3 - Lab test method
Result Turnaround Time
3-14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
3 mL
Minimum Volume
Not provided
Container
Lavender top (EDTA)
Collection Instructions
Invert several times to mix blood. Send whole blood specimen in original tube. Do not aliquot.
Patient Preparation
A previous hematopoietic stem cell transplant from an allogenic donor will interfere with testing.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 4 days |
| Frozen | 4 days |