Francisella tularensis Antibody, IgM and IgG, Technical Interpretation, Serum
Use
The test is designed to aid in the diagnosis of tularemia caused by Francisella tularensis, an intracellular, coccobacillary gram-negative bacterium and an obligate pathogen in animals and humans. The test is used to identify antibodies against F. tularensis, which may support a diagnosis of current or recent tularemia in patients who are IgM positive or seroconvert to IgM, or who are IgG positive in paired sera collected 2 to 3 weeks apart. F. tularensis infection may result from various routes, including inhalation of infected aerosols, ingestion of contaminated meat or water, animal contact, or arthropod bites.
Special Instructions
Not provided.
Limitations
False-negative results may occur if the specimen is collected too soon following the onset of symptoms, prior to the development of a detectable immune response. False-positive results may occur in patients with previous or concurrent Brucella infection. Cross-reactions with Yersinia, Salmonella, or Legionella species have been reported. IgM antibodies may remain detectable for years following disease resolution, which can confuse the interpretation related to current or recent infections.
New York Approved
Methodology
Automated Analyzer
Biomarkers
Francisella tularensis
Protein
LOINC Codes
- 93718-5 - F tular IgG+IgM Ser-Imp
- 93718-5 - F tular IgG+IgM Ser-Imp
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Only orderable as part of a profile. For more information see TULAB / Francisella tularensis Antibody, IgM and IgG, ELISA, Serum.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 30 days |