Gamma-Hydroxybutyric Acid (GHB), Serum/Plasma
Use
Detects gamma‑hydroxybutyric acid (GHB) in serum or plasma as a screening test. If the screen is non‑negative, a confirmatory test (FGHA) is reflexively performed at additional charge, supporting clinical interpretation of possible GHB exposure or abuse.
Special Instructions
This test is available in New York State. It uses a reflex testing algorithm: a non‑negative screen triggers reflex confirmatory testing (FGHA) for GHB. The methodology includes LC/MS/MS for screening and GC/MS for confirmation where appropriate.
Limitations
Serum gel tubes and plasma gel tubes are not acceptable. Performance and classification characteristics were developed by Labcorp and have not been cleared or approved by the FDA. The test is classified as an analyte‑specific reagent and not a FDA‑approved device.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 46085-7
- 46085-7
Result Turnaround Time
7-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
1.2 mL
Container
plain red‑top tube(s), plastic vial
Collection Instructions
Draw blood in a plain red‑top tube(s), serum gel tube is not acceptable. Spin down and send 5 mL of serum refrigerated in a plastic vial.
Causes for Rejection
serum gel tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient 72 hours |
| Refrigerated | Refrigerated 7 days |
| Frozen | Frozen 180 days |