Gastrin Immunostain, Technical Component Only
Use
Characterization of islet cell tumors and endocrine tumors of the gastrointestinal tract. Gastrin is a polypeptide hormone produced and secreted by G cells in the antral mucosa of the stomach and in the duodenum and upper jejunum. The hormone is a potent stimulant of acid secretion and also increases gastric motility. Gastrin staining can identify G cells in the antral stomach and help characterize some islet cell tumors and other neuroendocrine tumors.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only technical performance of the stain. If interpretation is required, order PATHC / Pathology Consultation for a full diagnostic evaluation or second opinion of the case. Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. Best practice is for paraffin sections to be cut within 6 weeks.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Gastrin
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block, or 2 unstained, positively charged glass slides per test ordered; sections 4-microns thick.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.