Grape, IgE, Serum
Use
This test is used for establishing a diagnosis of an allergy to grape by detecting IgE antibodies specific to grape allergens. It helps in defining the allergen responsible for allergic reactions, identifying allergens responsible for anaphylactic episodes, and confirming sensitization before starting immunotherapy. The test is useful in investigating the specificity of allergic reactions to insect venom, drugs, or chemical allergens. However, testing for IgE antibodies is not deemed useful in patients previously treated with immunotherapy or in cases where clinical management does not require allergen specificity.
Special Instructions
Not provided.
Limitations
Measurable levels of IgE antibodies can exist in individuals with clinically insignificant sensitivity, leading to false positives. Additionally, patients with markedly elevated serum IgE (>2500 kU/L) may experience nonspecific IgE binding to allergen solid phases. IgE antibody levels should be interpreted in the clinical context, particularly as they cannot determine residual clinical sensitivity post-immunotherapy.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
IgE specific to grape
Protein
LOINC Codes
- 6841-1 - Grape IgE Qn
- 6841-1 - Grape IgE Qn
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL, for more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Serum must not be grossly hemolyzed or lipemic.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |