Helicobacter pylori Culture with Antimicrobial Susceptibilities, Varies
Use
The test is useful for the recovery of Helicobacter pylori from gastric specimens and to perform antimicrobial susceptibility testing on the organism. This can guide appropriate treatment options, particularly by testing for susceptibility to antibiotics like amoxicillin, clarithromycin, levofloxacin, metronidazole, rifampin, and tetracycline. These findings are critical in formulating treatment plans for patients who have infections caused by Helicobacter pylori, which can lead to conditions such as chronic gastritis, peptic ulcer disease, or gastric neoplasia.
Special Instructions
Specimen must be received in the laboratory within 48 hours of collection. Preferred specimen is fresh tissue or biopsy from gastric or duodenal sources, stored in a sterile container. Specimen source with specific anatomic location must be provided. For associated tests and further diagnostic utilization options, refer to the Helicobacter pylori Diagnostic Algorithm.
Limitations
False-negative results may occur due to the fastidious nature of the organism and delays in specimen transportation. H. pylori requires selective media and specific growth conditions for culture, which may not completely reflect clinical efficacy of antimicrobial agents. In vitro susceptibility results should not be the sole basis for antimicrobial treatment decisions as clinical response can vary.
FDA ApprovedNew York Approved
Methodology
Culture-based
Biomarkers
LOINC Codes
- 587-6
- 587-6
Result Turnaround Time
7-28 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
0.5 x 0.2 x 0.2-cm sized piece of tissue
Minimum Volume
Not provided
Container
Sterile container
Collection Instructions
Acquire biopsied tissue; moisten with sterile saline
Causes for Rejection
Biopsy submitted in fluid other than sterile saline
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 48 hours |