Hematologic Disorders, Chromosome Hold, Varies

Casandra

Casandra Test Code MC23910Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID HOLDC

Hematologic Disorders, Chromosome Hold, Varies

Clinical Use

Use

This test is used for holding bone marrow or peripheral blood specimens in the laboratory, delaying chromosome analysis while a preliminary morphologic assessment is conducted. Conventional chromosome analysis is the gold standard for identifying common chromosome abnormalities in hematologic malignancies. Depending on the diagnosis, fluorescence in situ hybridization assays may also be used if they provide more informative insights about chromosome anomalies with prognostic significance, especially for plasma cell proliferative disorders.

Special Instructions

If the client notifies the laboratory that chromosome analysis is not necessary within the specified timeframe, the test can be canceled with a processing fee charged. Otherwise, chromosome analysis will be performed and charged accordingly. Ensure to contact the Cytogenetics Laboratory at 800-533-1710 by 3 p.m., within 2 business days after specimen collection for cancellation requests. Weekend communications can be deferred until Monday.

Limitations

This test does not cover fluorescence in situ hybridization (FISH) assays and may not be recommended for plasma cell neoplasms. The chromosome analysis is postponed until the preliminary morphologic assessment is complete, which can delay specific diagnosis. Chromosome analysis will not be performed if the specimen shows no evidence of malignancy, and additional testing like FISH might provide more relevant information depending on the case.

Test Details

New York Approved