Hemoglobin Electrophoresis Evaluation, Blood
Use
This test is useful for the diagnosis and classification of hemoglobin disorders, including thalassemias and hemoglobin variants. Hemoglobin electrophoresis is a critical component in identifying abnormal hemoglobin variants that can lead to clinical conditions such as thalassemias and sickling disorders.
Special Instructions
Not provided.
Limitations
Some hemoglobin variants and thalassemia conditions are not detectable by routine screening methods and may require molecular testing for accurate identification. Recent transfusions can affect results, particularly in hemoglobin electrophoresis and other stability or solubility studies. Proper communication of the patient's clinical history and prior therapies is essential for selecting the appropriate reflex tests.
New York Approved
Methodology
Multiple
Biomarkers
Unknown protein
Protein
LOINC Codes
- 94538-6 - Hgb HPLC + electrophoresis Pnl Bld
- 20572-4 - Hgb A MFr Bld Elph
- 32682-7 - Hgb F MFr Bld Elph
- 4552-6 - Hgb A2 MFr Bld Elph
- 24469-9 - Hgb XXX MFr Bld Elph
- 78748-1 - Hgb Fract Bld CE-Imp
- 49316-3 - Hgb Fract Bld Elph-Imp
Result Turnaround Time
2-25 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
1 mL (3 mL if multiplex ligation-dependent probe amplification needed)
Container
Lavender top (EDTA); Acceptable: Yellow top (ACD solution B)
Collection Instructions
Send whole blood specimen in original tube. Do not aliquot.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |