Hepatitis B Virus Core Total Antibodies Prenatal, Serum
Use
The test is useful for diagnosing recent or past hepatitis B in pregnant individuals and determining occult hepatitis B in hepatitis B virus carriers with negative test results for various hepatitis B markers. The test is specifically used to screen or test pregnant individuals who may have risk factors for hepatitis B virus infection. However, it should not be used for differentiating among different states of hepatitis B infection or for screening blood donor specimens.
Special Instructions
Not provided.
Limitations
The test should not be used for the screening or confirmatory testing of blood, plasma, and tissue donors as it is not licensed for these purposes by the FDA. It may not detect all infected individuals, and interference from high titer antibodies, streptavidin, or ruthenium is possible. False positives may occur due to various factors including the presence of sodium azide, or in patients with antibodies to other viruses. The test results should be considered alongside clinical history and other examinations.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
HBc Total Antibodies
Protein
LOINC Codes
- 13952-7 - HBV core Ab SerPl Ql IA
- 13952-7 - HBV core Ab SerPl Ql IA
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.7 mL
Minimum Volume
0.6 mL
Container
Plastic vial
Collection Instructions
Centrifuge blood collection tube per manufacturer's instructions and aliquot serum into a plastic vial.
Patient Preparation
For 24 hours before specimen collection, patient should not take multivitamins or dietary supplements containing biotin.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, and heat-inactivated specimen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 6 days |
| Frozen | 90 days |