Hepatitis B Virus Surface Antibody Prenatal, Qualitative/Quantitative, Serum
Use
This test is useful for identifying previous exposure to the hepatitis B virus in pregnant individuals and determining adequate immunity from hepatitis B vaccination during pregnancy. It is important for prenatal screening of pregnant individuals regardless of their risk factors for hepatitis B virus infection.
Special Instructions
The test is performed using an electrochemiluminescence immunoassay (ECLIA) and should not be used for screening asymptomatic, nonpregnant individuals or for diagnostic testing symptomatic individuals to evaluate post-vaccination immunity status or post-acute infection status of hepatitis B. Date of collection is required, and the patient should not take multivitamins or dietary supplements containing biotin (vitamin B7) 24 hours before specimen collection.
Limitations
This test has not been licensed by the FDA for the screening of blood, plasma, and tissue donors. It should be used in conjunction with the patient's medical history and other findings. The performance characteristics have not been established for certain specimen types, and interference from high titers of specific antibodies or biotin supplements can lead to false results.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 5193-8
- 5193-8
- 10900-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.7 mL
Minimum Volume
0.6 mL
Container
Serum gel tube, plastic vial for submission
Collection Instructions
Centrifuge blood collection tube per manufacturer's instructions. Aliquot serum into a plastic vial.
Patient Preparation
For 24 hours before specimen collection, patient should not take multivitamins or dietary supplements containing biotin (vitamin B7).
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 6 days |
| Frozen | 90 days |