Hepatitis E Virus IgG Antibody, Serum
Use
The test is used for the diagnosis of past exposure to hepatitis E virus (HEV). HEV is transmitted via the fecal-oral route, often from animals such as pigs to humans, and is endemic in parts of Asia, Africa, and Mexico. It's also present in developed countries, primarily affecting travelers. The detection of Anti-HEV IgG antibodies in serum helps determine if an individual had a past HEV infection, which can be important for assessing immune status, especially in those who have traveled to endemic regions.
Special Instructions
The date of collection is required for processing this test. Use the Gastroenterology and Hepatology Test Request form (T728), Infectious Disease Serology Test Request form (T916), or Microbiology Test Request form (T244) if not ordering electronically.
Limitations
A negative test does not rule out recent hepatitis E infection, especially if less than two months old, as the antibodies may not yet be detectable. Immunocompromised patients may experience prolonged viremia which can affect results. Factors such as hemolysis, lipemia, icterus, and specimens containing particulate matter can interfere with test performance. Performance characteristics have not been established for heat-inactivated specimens.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 49693-5
- 49693-5
Result Turnaround Time
1-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
Not provided
Container
Serum gel
Collection Instructions
Centrifuge blood collection tube per manufacturer's instructions within 2 hours of collection. Aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 24 hours |