Hepatitis E Virus RNA Detection and Quantification, Real-Time RT-PCR, Serum

Use

Hepatitis E virus (HEV) is a causative agent of acute self-limited or fulminant hepatitis and is primarily transmitted through waterborne and zoonotic infections. In immunocompetent individuals, it is mostly a self-limited infection. However, in immunocompromised patients, such as organ transplant recipients, HEV may become chronic. This test is crucial for detecting and confirming HEV infection in such individuals and for monitoring HEV RNA levels to assess response to antiviral therapy. It serves as an important tool for diagnosing acute or chronic HEV infection due to its limitations in serological testing for patients who are immunosuppressed.