Use

This test is used as a component of the initial evaluation of a patient presenting with hepatosplenomegaly. It serves as a screening test for select lysosomal and lipid storage disorders such as cerebrotendinous xanthomatosis, Gaucher disease, and Niemann-Pick disease types A, B, and C. Hepatosplenomegaly often presents due to chronic hepatic dysfunction or abnormal storage of lipids and other analytes. Screening aids in narrowing possible conditions due to the broad phenotypic variability and similarity of clinical features across different disorders.