Use

This test is useful for evaluating patients with a personal or family history suggestive of a hereditary pancreatic cancer syndrome. It assists in establishing a diagnosis of a hereditary pancreatic cancer syndrome, which enables targeted cancer surveillance based on the associated risks. By identifying genetic variants associated with an increased risk for pancreatic cancer, the test allows for predictive testing and appropriate screening of at-risk family members. It also informs therapeutic eligibility with poly adenosine diphosphate-ribose polymerase (PARP) inhibitors based on certain gene alterations such as BRCA1 and BRCA2.