Herpes Simplex Virus (HSV), Molecular Detection, PCR, Blood
Use
This qualitative molecular assay provides detection of HSV DNA in blood to aid in the rapid diagnosis of disseminated herpes simplex virus infection. It reports results as positive or negative for HSV‑1, HSV‑2, or HSV‑indeterminate, with an “invalid” result indicating inability to determine presence or absence of HSV DNA. Negative results do not rule out infection, and the test should not be used for screening asymptomatic individuals. An indeterminate result warrants repeat collection and testing by an alternate method if typing is required.
Special Instructions
Not provided.
Limitations
Designed only for patients with clinical history and symptoms consistent with HSV infection; it should not be used to screen asymptomatic individuals. A negative result does not eliminate the possibility of infection. Viral DNA detection may occur in asymptomatic viral shedding. An indeterminate result occurs when HSV DNA is detected but cannot be typed; an invalid result indicates inability to detect. Improper specimen collection, handling, or interfering substances may affect accuracy.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
HSV‑1
MicroorganismHSV‑2
Microorganism
LOINC Codes
- 93440-6 - HSV 1+2 DNA Pnl Bld NAA+n-prb
- 93439-8 - HSV1 DNA Bld Ql NAA+n-prb
- 93438-0 - HSV2 DNA Bld Ql NAA+n-prb
Result Turnaround Time
0-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.4 mL
Container
Lavender top (EDTA) tube
Collection Instructions
Send whole blood specimen in original tube. Do not aliquot.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days (preferred) |
| Frozen | 7 days |