Herpes Simplex Virus (HSV), Molecular Detection, PCR, Varies
Use
This test aids in the rapid diagnosis of herpes simplex virus (HSV) infections by detecting HSV DNA qualitatively in nonblood clinical specimens. HSV types 1 and 2, belonging to the Herpesviridae family, can cause a range of infections from mild stomatitis to severe disseminated disease. Clinical conditions associated with HSV include gingivostomatitis, keratitis, encephalitis, vesicular skin eruptions, aseptic meningitis, neonatal herpes, genital tract infections, and disseminated primary infection. The test results can rapidly support diagnosis when clinical findings suggest HSV infection.
Special Instructions
Not provided.
Limitations
The test may detect viral nucleic acid shedding in asymptomatic individuals, particularly from dermal or genital sites. Negative results do not eliminate the possibility of HSV infection. As this assay may provide an indeterminate result between HSV-1 and HSV-2, further typing with a new specimen may be necessary to differentiate. Proper patient history is necessary to interpret results accurately.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
HERPES SIMPLEX VIRUS (HSV)-1
MicroorganismHERPES SIMPLEX VIRUS (HSV)-2
Microorganism
LOINC Codes
- 94580-8 - HSV 1+2 DNA Pnl Spec NAA+n-prb
- 31208-2 - Specimen source
- 94581-6 - HSV1 DNA Spec Ql NAA+n-prb
- 94582-4 - HSV2 DNA Spec Ql NAA+n-prb
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Body Fluid
Volume
0.5 mL
Minimum Volume
Not provided
Container
Sterile container
Collection Instructions
Do not centrifuge.
Causes for Rejection
Calcium alginate-tipped swab, Wood swab, Transport swab containing gel, Formalin-fixed tissue, Heat-inactivated specimens, Dry/flocked ESwab.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 7 days |