Herpesvirus 7 IgG and IgM Antibody Panel, IFA
Use
Human Herpesvirus 7 (HHV-7), a close relative of HHV-6, is found in more than 85% of the population with transmission usually occurring in early childhood. Like HHV-6, HHV-7 is a cause of exanthem subitum (roseola infantum). The detection of HHV-7 specific IgG and IgM antibodies can be used to indicate recent infection. More than 80% of individuals in the general population exhibit HHV-7 IgG titers of greater than or equal to 1:20. However, IgG titers greater than 1:320 are suggestive of a recent HHV-7 infection. Similarly, identifying HHV-7 specific IgM is indicative of recent infection.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration (FDA); it has been developed and validated by Quest Diagnostics per CLIA regulations. The assay is used for clinical purposes but has not undergone full FDA review. IgG and IgM antibodies detected by this test are not indicative of the exact time of infection and should be interpreted in the context of clinical symptoms and other diagnostic procedures.
New York Approved
Methodology
Immunoassay (Immunofluorescence Assay)
Biomarkers
LOINC Codes
- 41842-6 - HHV7 IgG+IgM Pnl Titr Ser IF
- 26972-0 - HHV7 IgG Titr Ser IF
- 27177-5 - HHV7 IgM Titr Ser IF
Result Turnaround Time
3-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red or SST; Plastic vial
Collection Instructions
Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Centrifuge and send 1 mL serum in a screw-capped vial, shipped refrigerated.
Causes for Rejection
Gross hemolysis, gross lipemia, and gross icterus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |