Herpesvirus 7 IgG and IgM Antibody Panel, IFA

Casandra

Casandra Test Code MC90191Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID FH7GMCPT Code 86790

Herpesvirus 7 IgG and IgM Antibody Panel, IFA

Clinical Use

Use

Human Herpesvirus 7 (HHV-7), a close relative of HHV-6, is found in more than 85% of the population with transmission usually occurring in early childhood. Like HHV-6, HHV-7 is a cause of exanthem subitum (roseola infantum). The detection of HHV-7 specific IgG and IgM antibodies can be used to indicate recent infection. More than 80% of individuals in the general population exhibit HHV-7 IgG titers of greater than or equal to 1:20. However, IgG titers greater than 1:320 are suggestive of a recent HHV-7 infection. Similarly, identifying HHV-7 specific IgM is indicative of recent infection.

Special Instructions

For optimal specimen performance, it is advisable to use a plain red-top tube, or a serum gel tube can alternatively be used. The blood should be centrifuged, and then 1 mL of serum should be submitted in a screw-capped vial, shipped refrigerated.

Limitations

This test has not been cleared or approved by the US Food and Drug Administration (FDA); it has been developed and validated by Quest Diagnostics per CLIA regulations. The assay is used for clinical purposes but has not undergone full FDA review. IgG and IgM antibodies detected by this test are not indicative of the exact time of infection and should be interpreted in the context of clinical symptoms and other diagnostic procedures.

Test Details

New York Approved