HIV-1 and HIV-2 Antigen and Antibody Routine Screen, Plasma

Casandra

Casandra Test Code MC84355Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID HVCOPCPT Codes 0475, 86701, 86702, 87389, 87536

HIV-1 and HIV-2 Antigen and Antibody Routine Screen, Plasma

Clinical Use

Use

Screening for HIV-1 and HIV-2 infection in nonsymptomatic, nonpregnant individuals older than 2 years. The test is an essential tool in diagnosing early HIV infection by detecting both HIV antigen and antibodies. It is used in clinical settings to identify individuals who might need further testing and appropriate intervention, especially critical for managing and preventing the spread of HIV. However, this test is not suitable for diagnosing or confirming HIV infections in blood donations due to different regulatory requirements in this context.

Special Instructions

Not provided.

Limitations

This assay is not licensed for the screening of blood, plasma, cells, tissues, and cellular and tissue-based product donors. A reactive result does not differentiate among reactivities with HIV-1 p24 antigen, HIV-1 antibody, and HIV-2 antibody. The test does not confirm the presence of HIV-1 or HIV-2 infection. For diagnostic accuracy, reactive screening results should be confirmed with supplemental tests. The performance of this assay is influenced by the prevalence of HIV in the population being tested, which affects both its predictive value and potential false-positive rate.

Test Details

New York Approved