HIV-1/HIV-2 RNA Detection Prenatal, Plasma
Use
This test is vital for diagnosing HIV-1 and/or HIV-2 infection in pregnant individuals who have indeterminate or inconclusive HIV serologic test results or who are suspected to be in the acute/early phase of infection. It provides critical information for initiating timely interventions to prevent perinatal transmission of HIV.
Special Instructions
Not provided.
Limitations
This test is not licensed by the FDA as a screening test for donors of blood, cells, tissues, or tissue products. An 'Undetected' result may not rule out HIV infection, especially if the collection happened less than 10 days post-exposure or if the patient harbors a rare HIV variant. Improper specimen storage/processing may lead to false negatives.
FDA ApprovedNew York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
HIV-1
MicroorganismHIV-2
Microorganism
LOINC Codes
- 96557-4 - HIV 1 + 2 RNA Pnl SerPl NAA+probe
- 25835-0 - HIV1 RNA SerPl Ql NAA+probe
- 69353-1 - HIV 2 RNA SerPl Ql NAA+probe
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1.5 mL
Minimum Volume
0.8 mL
Container
Plastic vial
Collection Instructions
Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial. Freeze aliquoted plasma for shipment.
Storage Instructions
Ship specimen frozen on dry ice. If shipment is delayed more than 24 hours, freeze plasma at -20 to -80 degrees C until shipment.
Causes for Rejection
Gross hemolysis, gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 6 days |
| Frozen | 40 days |