HLA B High Resolution
Use
HLA B High Resolution testing is instrumental in transplant matching and monitoring, disease association studies, and pharmacogenomics analysis. It provides high-resolution typing necessary for accurate donor-recipient match assessments and immunogenetic research. This test is widely used for determining genetic compatibility and identifying potential rejection risks in transplant procedures. Understanding the HLA B genotype aids in selecting optimal medication regimens, predicting adverse drug reactions, and studying disease susceptibility linked to HLA variations.
Special Instructions
Histocompatibility Lab Transplant Testing Requisition is required for sample processing. The test involves drawing blood in a lavender-top EDTA tube. The collected specimen should be sent at ambient temperature to ensure sample integrity. Ensuring that all required forms and requisitions are completed is necessary to avoid testing delays.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration. The high-resolution HLA typing may not detect rare or novel alleles, potentially impacting matching accuracy. Hemolyzed specimens will be rejected, which can result in delayed testing. The test is dependent on sample quality and volume received; insufficient volume may necessitate recollection. The turnaround time can vary, and retesting may be required, which affects the availability of results.
New York Approved
Methodology
PCR-based (Direct DNA Sequencing)
Biomarkers
LOINC Codes
- 45028-8
- 45028-8
- 48767-8
Result Turnaround Time
7-11 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
14 mL
Minimum Volume
5 mL
Container
Lavender-top (EDTA) tube
Collection Instructions
Draw blood in a lavender-top (EDTA) tube(s).
Causes for Rejection
Hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |