HLA C High Resolution
Use
This test is used for high-resolution typing of the HLA-C gene. It is particularly useful in the context of tissue typing for organ transplantation, bone marrow transplantation, and for disease association studies. High-resolution HLA typing provides detailed information about HLA alleles, which can impact graft survival, transplant-related complications, and the efficacy of targeted therapies. Accurate HLA typing is critical for matching donors and recipients to improve outcomes and reduce the risk of transplant rejection.
Special Instructions
A Histocompatibility Lab Transplant Testing Requisition is required for this test. Blood should be drawn in a lavender-top (EDTA) tube, and sent at ambient temperature.
Limitations
This test was developed and its performance characteristics determined by Versiti Wisconsin, Inc., and it has not been cleared or approved by the FDA. The test is intended for clinical use and not for investigative or research purposes. Interpretations should be made in conjunction with the overall clinical context. Hemolysis in the specimen can lead to rejection; thus, meticulous specimen handling is required. Additionally, inherent biological variation like sequence similarities between HLA alleles may complicate results interpretation.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 45031-2
- 45031-2
- 48767-8
Result Turnaround Time
7-11 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
14 mL
Minimum Volume
5 mL
Container
Lavender-top (EDTA) tube
Collection Instructions
Draw blood in a lavender-top (EDTA) tube(s).
Storage Instructions
Send at ambient temperature.
Causes for Rejection
Hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |