Horse Dander, IgE, Serum
Use
The Horse Dander IgE test is used for diagnosing an allergy to horse dander and identifying the allergen responsible for eliciting signs and symptoms. It is specifically helpful for patients showing allergic responses to horse dander, assisting in confirming sensitization prior to immunotherapy, and investigating allergic reactions to insect venom allergens, drugs, or chemical allergens. The test measures the IgE antibodies in serum to support the diagnosis of allergic diseases associated with such exposures.
Special Instructions
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients whose medical management is not dependent on allergen specificity identification. The test requires a serum specimen with proper collection instructions, including centrifuging and aliquoting serum into a plastic vial for submission.
Limitations
This test may not provide accurate indications of allergen sensitivity in some patients with clinically insignificant sensitivity who may show measurable levels of IgE antibodies. False-positive results can occur in patients with high serum IgE (>2500 kU/L) due to nonspecific binding. It is important to interpret results within the clinical context, considering potential diagnostic confusion, improper specimen handling, inappropriate test selection, and interfering substances.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6143-2
- 6143-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis is OK; Gross lipemia is OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |