Human Herpes Virus, Type 8 (HHV-8) Immunostain, Technical Component Only
Use
This test is useful for identifying human herpes virus type 8 infection, which can lead to lymphoproliferative diseases or other neoplasms, notably in patients with HIV. Such neoplasms include the plasma cell variant of Castleman disease, Kaposi sarcoma, and primary effusion lymphoma. The presence of HHV-8 can be a critical determinant in diagnosing these conditions.
Special Instructions
Not provided.
Limitations
The test does not include pathologist interpretation, only technical performance of the stain. Interpretation should be conducted by a qualified pathologist in the context of the patient's clinical history and other diagnostic tests. The age of cut paraffin sections can affect immunoreactivity, which is antigen-dependent. Glass slides may be affected by environmental conditions, impacting slide staining results.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides