Human Papillomavirus (HPV) Low Risk, In Situ Hybridization
Use
This test is useful for the detection of human papillomavirus from low-risk genotypes (6, 11). Human papillomavirus infections with these genotypes can cause benign hyperplasia, such as condylomas and papillomas. The test aids in identifying the presence of HPV types that are associated with low-risk conditions.
Special Instructions
A pathology/diagnostic report and a brief history are required. If not ordering electronically, complete, print, and send one of the following forms with the specimen: Oncology Test Request (T729), Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763). Attach the green 'Attention Pathology' address label (T498) to the transport container before mailing.
Limitations
Age of a cut paraffin section can affect staining quality. It is best practice for paraffin sections to be cut within 6 weeks to avoid loss of quality. Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, and ProbeOn slides are causes for rejection.
New York Approved
Methodology
Chromosomal / Cytogenetics (ISH)
Biomarkers
LOINC Codes
- 50595-8
- 19139-5
- 81178-6
- 62364-5
- 80398-1
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block, or 5 unstained glass slides with 4-microns, positively charged, formalin-fixed, paraffin-embedded tissue.
Storage Instructions
Ambient (preferred), or refrigerated.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient |
| Refrigerated | Yes |