Human Placental Lactogen (HPL)
Use
Human placental lactogen (hPL; chorionic somatomammotropin) is a 21,000 Da polypeptide produced during pregnancy by placental trophoblastic cells. The level of hPL in maternal serum is directly related to placental function and fetal well-being. Human placental lactogen is detected about 6 weeks after conception and its concentration increases gradually to peak levels until about the 34th week, where it remains stable for the remainder of the pregnancy. Consistently low levels throughout pregnancy or a sudden drop in serial determinations are an indication of fetal distress.
Special Instructions
Centrifuge the specimen at 3000 rpm for 10 minutes immediately after collection. Aliquot 1 mL of serum into a plastic vial and freeze immediately. The serum must be sent frozen.
Limitations
The performance characteristics of this assay were validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. However, the results of this assay can be used for clinical diagnosis without FDA approval.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 2104-8
Result Turnaround Time
3-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red top
Collection Instructions
Centrifuge at 3000 rpm for 10 minutes. Aliquot 1 mL of serum into a plastic vial and freeze immediately.
Storage Instructions
Send serum frozen.
Causes for Rejection
Hemolysis, Icterus, Lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 90 days |